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Potential association between proton pump inhibitor (PPI) use and pneumonia in dogs
A putative link is reasonably well-documented in people: PLoS One. 2015 Jun 4;10(6):e0128004. doi: 10.1371/journal.pone.0128004. eCollection 2015.Risk of community-acquired pneumonia with outpatient proton-pump inhibitor therapy: a systematic review and meta-analysis.Lambert AA1, Lam JO2, Paik JJ3, Ugarte-Gil C4, Drummond MB1, Crowell TA5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456166/ ‘Outpatient PPI use is associated with a 1.5-fold increased risk of community-acquired pneumonia, … Continue reading
Lung ultrasound: contusions, interstitial syndrome, A, B, C, E, I and Z-lines explored
I reckon lung ultrasound must be one of the most profound developments in veterinary medicine during my career. The facility to diagnose rapidly, and with high degree of confidence, pneumonia, pulmonary oedema, contusions, pneumothorax and neoplasia is a phenomenal advance. Having arrived in our tool-kit in the last 10 years, this is still an evolving field. In this … Continue reading
Gabapentin as a sedative/anxiolytic prior to ultrasonography in cats
Gabepentin is an enormously useful drug to facilitate ultrasonography in cats. I’m sure most of you are aware of this by now but it’s worth publicising a little more because, to get best effect, the use of gabapentin needs to be planned in advance of the day of scanning. J Am Vet Med Assoc. … Continue reading
SOFA vs SIRS and sonographic features of septic shock in dogs
In human medicine concepts in sepsis have evolved. SIRS: In 2016, a new consensus termed Sepsis-3 removed the concept of SIRS from the sepsis definition and replaced it with the SOFA (Sequential [Sepsis-Related] Organ Failure Assessment) score. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016; 315(8):801-10 (ISSN: 1538-3598) Singer M; … Continue reading
